Welcome to IMM250H1S 2023!
Goals for This Lecture:
• Course Business (Dr. Singh)
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• History of Immunology (Dr. Clemenza)
• Overview of the Immune System (Dr. Clemenza)
Course Co- coordinators:
The IMM250S Team
Email: Office Hours: Tuesday, 9-10am (MS 7318)
Dr. Jasty Singh
Course Lecturers:
All postings (lecture material and announcements) will be done on Quercus. Please check Quercus regularly.
About This Course
IMM250 is a required course for all immunology programs, however it is designed to fulfill breadth requirements and is an appropriate choice for students in other science or humanities programs. Development of writing skills through the composition of a science article for the general public is one objective of this course.
Recommended Preparation: BIO120H, BIO130H Lectures:
Will be released 9AM, Monday each week, as per the course schedule.
Tutorials:
Tutorial I (pre-midterm): February 10, 9-11am ET
Tutorial II (term paper): March 21, 10am-12pm ET
NB: Participation is not mandatory but recommended. The tutorial slides and recordings will be posted on Quercus the day after each tutorial takes place.
Required Textbook:
Custom-built interactive “Surveying the immune system” by L. Clemenza and W. Tamminen, included in the Top Hat IMM250 course pack
What you are going to learn in this course: our strategy
Less memorization
More conceptual understanding
Induce deeper understanding
Associate a case-study
Pick newsworthy immunity stories
Explain the pertinent immunology
Lecture Schedule
Tentative Topic
Course Business & Overview of the Immune Response
Innate Immunity: the first line of defense to infection
Dr. . 23 Jan. 30 Feb. 6
Feb. 27 Mar. 6 Mar. 13 Mar. 20
Innate immunity: Soluble and cellular mediators Features of the Adaptive Immune Response Generation of the adaptive immune response
T Cell Responses in Host Defense
The Antibody Response
Immunology of the Gastrointestinal Tract Immunopathology
Guest lecture – Influenza infection
Dr. . Singh
Dr. . . Watts
MIDTERM TEST (ONLINE – 2hrs; 9AM-9PM)
NO CLASS – Reading Week
Guest Lecture: Vaccines – Harnessing the Adaptive Immune Response
Dr. Tamminen
Apr. 11-28
FINAL ASSESSMENT PERIOD – Final Assessment Date TBA
Evaluation Summary and Event Dates:
Assessment
% of Grade
Midterm Test 30% Final Assessment 35% Top Hat Participation 10% Assignment: Science & Society Paper 25%
February 13, 2023 (online) TBA
March 27, 2023 (11:59 pm)
Midterm Test: Covers lectures 1-5, multiple choice format
Final Assessment: Cumulative, although biased towards second half of the
course, multiple choice format
*Please see course syllabus for complete details on missed assessment policies.
Science & Society Assignment – Paper Topic:
“Monkeypox Virus: The New Old Outbreak?”
The purpose of this assignment is for you to:
• Learn how to find both academic/non-academic sources and summarize
• Build a “story” for a general readership with or without a background in
• Think about a scientific problem from a multidimensional perspective
Due date: March 27, 11:59 PM ET
Your paper will be assessed using the criteria indicated in
the assignment-associated rubric (see syllabus)
There will be a tutorial (March 21; 10am-12pm ET) and a number of extra TA office hours dedicated to assignment requirements and assessment criteria.
Not just a course assignment, but also an opportunity to publish your work…
…the winning paper from IMM250H1F and IMM250H1S will be published in the Fall 2023 issue of IMMpress Magazine!
https://www.immpressmagazine.com/
DO NOT PLAGIARIZE
• Your term paper will be subjected to “ Turnitin” or other originality check analysis.
• You will be given the chance to check your originality score prior to the final submission of your paper.
• We recommend to check your originality score at least 24 hours before submission deadline.
• It is NOT acceptable to copy & paste information from source material into your term paper.
• This is plagiarism. Your paper must be IN YOUR OWN WORDS. *Familiarize yourself with the Code of Behavior on Academic Matters!
In-class response system and interactive textbook
Top Hat is required and includes:
• Classroomresponse
• Custom-built interactive Immunology
textbook Cost: $22 + tax
Join Code: 385911**
**Use your University of Toronto email address to join Top Hat
How Top Hat Grading (10% of Grade)
% Questions answered
Class Participation Mark (/10%)
0% 0% 5 ≤ % answered < 10 1% 10 ≤ % answered < 20 2% 20 ≤ % answered < 30 3% 4%
Textbook Chapters:
• Assigned for each lecture
• “Homework mode” opens up 9AM the week
of the corresponding lecture, closes Tuesday
9AM the week after.
• 0.5 marks participation, 0.5 marks correctness
per question
• No accommodation for missed Top Hat
participation
30 ≤ % answered < 40
40 ≤ % answered < 50
50 ≤ % answered < 60 6% 60 ≤ % answered < 70 7% 70 ≤ % answered < 80 8%
9% 90 ≤ % answered ≤ 100 10%
80 ≤ % answered < 90
Appropriate Use of Course Material
This course will be recorded on video and will be available to students in the course for viewing remotely. Note that all course materials are the intellectual property of the course instructors, and they are made available to you for your personal use in this course. Sharing, posting, selling or using this material outside of your personal use in this course is not permitted under any circumstances and is considered an infringement of intellectual property rights. According to intellectual property laws, not asking permission constitutes stealing.
For questions about recording and use of videos in which you appear (i.e. Tutorial chat/mic), please contact Drs. Singh and Buechler
Tips to Succeed in IMM250
• Read the course syllabus in its entirety and understand the course policies.
• Watch the lecture videos weekly and take notes.
• Complete weekly Top Hat homework questions.
• Attend and participate in tutorials (midterm and term paper).
• Attend EXTRA TA office hours (schedule will be posted on
• If you find that you are having trouble with concepts, please seek help as early as possible on Quercus Discussions or in office hours. Take advantage of help & ask questions!
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